The School of Cardiovascular and Metabolic Medicine & Sciences (SCMMS) provides an outstanding multi-disciplinary environment for the pursuit of cutting-edge cardiovascular and metabolic research. We study the fundamental molecular, cellular, and physiological processes that underly normal and abnormal cardiovascular and metabolic function and drive the translation of this strong basic science into advances in clinical practice. Our research focuses on four main Themes (Cardiac, Vascular, Cardiometabolic, Diabetes & Obesity), with two cross-cutting Themes (Basic and Clinical). The School is led by Professor Mauro Giacca and comprises over 65 clinical and non-clinical academic groups, hosting 400 personnel and 110 PhD students. 

 

Our community of world-renowned researchers and educators have access to state-of-the art core facilities and expertise, including facilities for high-throughput screening and high content imaging, multimodality in vivo imaging, proteomics, integrative physiology and viral & non-viral vector production. 

 

The School activities are carried out at three main locations: James Black Centre in Denmark Hill, St Thomas’s Hospital and Franklin-Wilkins Building in South Bank and the Hodgkin Building and New Hunt House/Randal Centre in Guy’s Campus. As part of King’s Health Partners, we have an excellent environment for basic-clinical interaction and a strong focus on mentoring and career development. The School hosts the British Heart Foundation Centre of Research Excellence at King’s, which brings together a unique range of internationally recognised scientists and clinicians from across the School and King’s College London. 

 

More information: https://www.kcl.ac.uk/scmms. 

 

This is an exciting opportunity to work on cardio-immunology within King’s BHF Centre of Excellence. Myocardial infarction is the commonest cause of heart failure and there is compelling evidence implicating excessive inflammation as a key contributor. Cardiac-resident leucocyte subsets are important mediators of the inflammatory response to cardiac injury, but it is not clear how signalling in these cells is regulated. 

 

The project aims to delineate signalling in leucocytes after myocardial infarction using in vivo models, in vitro experiments, and multi-platform ‘omics’ approaches. These studies will provide invaluable knowledge on the regulation of inflammation after MI. We aim to identify and target novel signalling pathways and genomic and transcriptional regulators of inflammation that we can translate to the bedside to alleviate progression to heart failure.

 

We are seeking a motivated and enthusiastic candidate to join our pre-clinical and translational research. The successful applicant will be expected to develop and undertake research of high quality consistent with the aims of the project. They will contribute to all facets of the lab, including managing specific work packages and working as part of a multi-disciplinary team.  

 

This is a full-time post (35 hours per week), and you will be offered a fixed term contract until 31st March 2028.

 

Research staff at King’s are entitled to at least 10 days per year (pro-rata) for professional development. This entitlement, from the  Concordat to Support the Career Development of Researchers, applies to Postdocs, Research Assistants, Research and Teaching Technicians, Teaching Fellows and AEP equivalent up to and including grade 7. Visit the  Centre for Research Staff Development for more information.