The Centre for Human & Applied Physiological Sciences (CHAPS) is situated within the School of Basic & Medical Biosciences(within the Faculty of Life Sciences and Medicine), which is led by Professor Mathias Gautel and comprises five departments with a wide range of expertise and interests. Using a bench to bedside approach, the School aims to answer fundamental questions about biology in health and disease and apply this knowledge to the development of new and innovative clinical practise, alongside providing a rigorous academic programme for students.

Dr Seaborne’s group investigates the molecular and cellular mechanisms underpinning muscle biology, in the context of health and disease. His labs interests have begun to explore the analysis of multi-molecule data sets to understand how striated muscle is regulated during health, disease and stress-response contexts.

 

The successful candidate will lead computational lab analysis work across multiple projects, largely focussing on the perturbation of skeletal muscle cells (myofibres) during periods of environmental and/or genetic influence (ageing, amyotrophic lateral sclerosis, sex differences…) and in the analysis of single myofiber data sets. Importantly, the candidate will be required to use current and bespoke computational and bioinformatic pipelines to analyse these data sets, as well as possibly modify or develop their own approaches to reliably and accurately analyse these data.

 

This is a 12 month full time on campus position (Guys Campus, London Bridge) starting no earlier than the 2 February 2026.