Overview
Post-doctoral Research Associate – Strand, London, WC2R 2LS
About Us
Applications are invited for a Post-Doctoral Researcher Associate to work in the laboratory of Professor Malcolm Logan based in the Randall Centre for Cell and Molecular Biophysics, which is part of the School of Basic & Biomedical Sciences. We sit in the Faculty of Life Sciences & Medicine and we are based at the Guy’s Campus of King’s College London.
The Randall Centre, King’s College London is a vibrant research environment, hosting labs working in burgeoning fields in biomedicine. Our research addresses fundamental biological questions at the interface between the physical and biomedical sciences focused on cell motility and the cytoskeleton, muscle signalling, stem cells and developmental biology.
About the role
Manipulating a morphogen in time and space
A morphogen is a special class of signalling molecule that acts during embryonic development to generate a variety of cell states. In response to distinct threshold levels of morphogen signalling, cells follow different fates and form different structures. Therefore, within a given territory, a single morphogen can generate multiple outcomes.
This project will experimentally study how morphogens work and, more specifically, how their activity can be modulated during embryonic development to shape anatomical structures. This is an issue important for evolution of morphological diversity across different species and understanding the origins of congenital birth defects.
In this project, using the chick embryo model, will create experimental situations in which cells of the limb bud are exposed to low, intermediate, or high physiological levels of the morphogen, SHH, and we will modulate the length of time cells are exposed to these levels of signalling. Are you allergic to egg? This role would not be compatible for someone who has an egg allergy.
This is a full time (35 hours per week), and you will be offered a fixed term contract until 30/06/2028, starting no sooner than 1st July 2025.
This is a laboratory-based role and as such it needs to be performed on site.
